It might fit, but the lower control arm bolt on the Highlander is picky with clearances. At least that's based on what I know. Double check before anything semi-permanent.I'm replacing the donut spare on my Toyota Highlander and found a brand-new 17" wheel and tire from a 2021 Sienna, the specs are close, but will that 17" clear the Highlander's rear caliper and lower control arm bolt?